Recently, I tried binding Combo to scroll down as well as 4. I also had set it to instant cast. Now, every time I open the game, it gets set back to default instead of instant, and there's also a chance it forgets the scroll down bind, but that's seemingly inconsistent. It's extremely annoying and it's killed me thrice. I had a similar issue a few months back when I was trying to bind Flog to scroll up, where it would reset, and eventually I just gave up on getting it to stay.