This one would be nice to have fixed because the most convenient key for cancelling abilities for me would be melee, but I'd like to have the option to change it for the specific heroes that are actually able to melee during an ability (Dynamo, Grey Talon, Kelvin)
It's also worth mentioning that Ivy, Vindicta, McGinnis and Viscous ignore the cancel ability hotkey entirely and only cancel their flights via pressing the ability again, even though I have the "Allow Canceling Abilities with the Ability Key" setting turned off. I assume this is due to the default ability cancel key being spacebar, and they need to be able to use spacebar to jump/ascend during their abilities, but since I changed my cancel hotkey there's no interference and no reason not to just use the hotkey I specify.