mouse 4/5 ability not working

[qwezero3]

sometimes in middle of match my ability not working with mouse button 4/5, i need to dc and reconnect to fix it

 

[naaavvv]

i have had the same issue. i thought it was a problem with my mouse, but the buttons worked outside of the game

 

[fluffyblankie]

I also have the same issue, when it happens you can actually see the button getting pressed down but the ability doesn't get used