I do notice the audio issue coincide with frame drop, but it happens quite inconsistently to me. last night i did some tinkering I found that changing speaker configuration to 2 speakers helps to somewhat reduce this issue for me.
I experience random audio issue that makes the game unbearable. theres no clear casue for this issue. it often happens inmid- late game. but i cannot consistentently replicate the issue but it happens quite often
here is an example